Monocyte Chemoattractant Protein 1 Does Not Contribute to Protective Immunity against Pneumococcal Pneumonia
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چکیده
منابع مشابه
Eotaxin and monocyte chemoattractant protein-1 in chronic eosinophilic pneumonia.
Chronic eosinophilic pneumonia (CEP) is characterized by chronic or recurrent pulmonary infiltrates with eosinophils, but the precise mechanism of eosinophil accumulation has not been fully elucidated. Eotaxin is one of the CC chemokines that selectively recruits eosinophils and contributes to the pathogenesis of allergic airway diseases including asthma, but its roles in pathogenesis of CEP ha...
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متن کاملMonocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant.
We have utilized a transendothelial lymphocyte chemotaxis assay to identify and purify a lymphocyte chemoattractant in supernatants of mitogen-stimulated peripheral blood mononuclear cells. Amino acid sequence analysis revealed identity with monocyte chemoattractant protein 1 (MCP-1), a chemoattractant previously thought to be specific for monocytes. Recombinant MCP-1 is chemoattractive for pur...
متن کاملMonocyte chemoattractant protein-1 derived from biliary innate immunity contributes to hepatic fibrogenesis.
AIMS Monocyte chemoattractant protein-1 (MCP-1) is a major chemotactic factor for hepatic stellate cells (HSCs) associated with hepatic fibrosis. In this study, among several fibrogenetic factors derived from biliary epithelial cells (BECs), MCP-1 produced by the biliary innate immune system was found to be most critical in the histogenesis of hepatic fibrogenesis. METHODS Using cultured huma...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2006
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00977-06